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The beneficial effect of intravenous thrombolytic therapy in patients with acute ischemic stroke attributable to internal carotid artery (ICA) occlusion remains unclear. A multicentric study gave new data on this topic. According to Italian investigators: in patients with stroke attributable to ICA occlusion, thrombolytic therapy,  results in a significant reduction in the proportion of patients dependent in activities of daily living. Increases in death and any intracranial bleeding were the trade-offs for this clinical benefit.


The recent paper published on Stroke reported how the kind of emergency transport adopted in the Austrian Alps was associated to specific chances to benefit fromclot busters

Helicopter Transport of Stroke Patients and Its Influence on Thrombolysis Rates

Data From the Austrian Stroke Unit Registry

Veronika Reiner-Deitemyer, MD; Yvonne Teuschl, PhD; Karl Matz, MD; Martina Reiter, MD; Raoul Eckhardt, MD; Leonhard Seyfang, MSc; Claudia Tatschl, MD; Michael Brainin, MD; for the Austrian Stroke Unit Registry Collaborators

From the Center of Clinical Neurosciences, Danube University Krems and Department of Neurology, Danube Clinic Tulln, Austria.

The results, from the largest series of cervical artery dissection database, suggest that hypertension, although less prevalent than in patients with a non-dissection related stroke, could be a risk factor of dissection, whereas hypercholesterolemia, obesity, and overweightness are inversely associated with dissection.

From Louisiana a new survey on dabigatran published on circulation in january : Dabigatran is a reasonable alternative to warfarin in patients requiring cardioversion.

Microbubbles filled with xenon or other inhert gases as a drug delivery means in acute stroke are periodically reported in medical journals (circulation 2010) or newspapers as the latest frontier. This week the activities of the University College in London and Cincinnati/Houston University raised the attention of scientific journalists see at New Scientist and Daily Mail. But don’t panic this in US was just another experimental animal model. As usual with bubbles also Italians are there.

As reported by a recent paper on Stroke MAs with atrial fibrillation have a higher stroke recurrence risk and more severe recurrences than do NHWs but no difference in all-cause mortality. Aggressive stroke prevention measures focused on MAs are warranted.

The leading joiurnals in stroke medicine are 4: Stroke (US based, with impact factor 7.041), Cerebrovascular Diseases (Germany based IF 3.5), Stroke and Cerebrovascular disease (pacific area IF na), International Journal of Stroke with impact fator 2.87 (world stroke soc.).

Marc Fisher 2010
Vice Editor
Karen Furie

Associate Editors
Pierre Amarenco—European Clinical
Kennedy R. Lees—European Clinical
Eng Lo—Basic Science
Wolf Schäbitz—Basic Science
K.S. Lawrence Wong—Asia-Pacific Clinical

Cerebrovascular disease
Hennerici M.G. (Mannheim)
Associate Editors

S. Davis, Melbourne
J.P. Mohr, New York, N.Y.
Y. Shinohara, Tokyo
N. Venketasubramanian, Singapore

Stroke and cerebrovascular disease
José Biller, MD, FACP, FAAN, FAHA
Professor and Chairman, Loyola University Chicago, Stritch School of
Medicine, Department of Neurology, Bldg. 105, 2160 South First Avenue,
Maywood, IL 60153
Shinichiro Uchiyama, MD, PhD, FAHA
Professor and Chairman, Department of Neurology Tokyo Women’s Medical
University c/o The Japan Stroke Society, 4F Maruishi Building, 1-10-4
Kaji-cho, Chiyoda-ku, Tokyo 101-0044, Japan

Intern journ of stroke
Geoffrey A. Donnan
Professor of Neurology, University of Melbourne

Associate Editors
Andrei Alexandrov
Peter Rothwell
Conrado Estol

Stroke Declines From the Second to the Third Leading Organ- and Disease-Specific Cause of Death in the United States.

With stroke death rates decreasing substantially in the United States from 1996 to 2005, stroke moved from the second to the third leading organ- and disease-specific cause of death. For details look at Stroke the paper by Amytis Towfighi, MD; Bruce Ovbiagele, MD, MS Jeffrey L. Saver, MD.

Marc Fisher, the New Editor-in-Chief of Stroke

..Few candidates have been as prepared and qualified as the newly appointed Editor-in-Chief of Stroke, Marc Fisher, who will be taking over the helm and receiving new manuscripts as of July 1, 2010…  Vladimir Hachinski

January 2019
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