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In 2011 SITS enrollment  is approaching 50,000 patients. This number of patients is important to enable an appriate analyses of the benefit and safety of thrombolysis in subgroups such as in the elderly (recent SITS and SITS-VISTA publications in Lancet Neurology and Stroke) and in a later time window (recently in Lancet Neurology). Alse mechanical means of disostruction will be included in the registry.


The results, from the largest series of cervical artery dissection database, suggest that hypertension, although less prevalent than in patients with a non-dissection related stroke, could be a risk factor of dissection, whereas hypercholesterolemia, obesity, and overweightness are inversely associated with dissection.

In press the results of Fori study the multi centric italian registry on PFO. See Risk of Recurrent Cerebrovascular Events in Patients with Cryptogenic Stroke or Transient Ischemic Attack and Patent Foramen Ovale: The FORI (Foramen Ovale Registro Italiano) Study
Paciaroni et al Cerebrovasc Dis 2011;31:109-116