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TICH-2 trial – Tranexamic acid for IntraCerebral Haemorrhage 2

investigator meeting italy , Mantova 19 Nov 2014 hosting Alfonso Ciccone

  • The trial is funded by the NIHR HTA
  • The trial opened in March 2013 and will run until February 2017
  • The University of Nottingham is acting as trial sponsor
  • The trial is live and recruitment is ongoing, with 682 participants so far
  • Start up phase — March 2013
  • Main phase — April 2014
  • New sites welcome in the UK and internationally

For further information please contact us.

Trial Manager: Hayley Foster <>
Chief Investigator: Dr Nikola Sprigg <>
Nottingham Stroke Trials Office:








Seems more and more evident that  levels of air pollution considered safe by health care authorities such as WHO can contribute to higher rates of cognitive decline, stroke, and heart attack, according to many paper recently published.

The beneficial effect of intravenous thrombolytic therapy in patients with acute ischemic stroke attributable to internal carotid artery (ICA) occlusion remains unclear. A multicentric study gave new data on this topic. According to Italian investigators: in patients with stroke attributable to ICA occlusion, thrombolytic therapy,  results in a significant reduction in the proportion of patients dependent in activities of daily living. Increases in death and any intracranial bleeding were the trade-offs for this clinical benefit.